Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/273967348?client_source=feed&format=rss
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Monday, December 31, 2012
2013 Sugar Bowl: Florida's Matt Elam declares for NFL Draft
The strong safety for the No. 3 Gators will forego his senior season to enter April's draft.
With a first-round grade from NFL scouts, it was an easy decision for Matt Elam to enter the NFL Draft. Florida's safety will forego his senior season to hear his name called by NFL commissioner Roger Goodell come April. The decision comes just over two weeks before the Jan. 15 deadline for underclassmen to declare for the draft.
In his second season as a starter for the Gators, Elam notched four interceptions and 65 tackles as a member of the nation's 3rd-ranked defense. The Gators allowed just 12.9 points per game, trailing only title contenders Alabama and Notre Dame.
Elam, a native of Palm Beach, Fla., has received first-round grades from both of CBS' college football analysts. In the initial mock draft, Rob Rang has Elam going 29th and Dane Brugler has him going 25th. Attending William T. Dwyer High School in Palm Beach, Elam played both sides of the ball before settling in at safety for Florida.
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Source: http://tampabay.sbnation.com/2012/12/30/3818448/sugar-bowl-2013
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Fire The Head of Social Media And Make These 10 Wishes Come True
A joyous moment has come — the idea that you need a director of social media is beginning to lose its myth status. For me, it says that maybe in 2013 some businesses may stop obsessing about how to centralize “social,” and instead just get the work done. Companies with social media directors have a problem. Mostly, they just don’t get it. Or worse, they do get it but to decentralize the corporate, top-down structure would actually disrupt the business and force some change. So here are 10 wishes for the enterprise that thinks they still need one person to organize the company’s tweets, check-ins or whatever. This is by no means a final list. Start talking to each other – who cares how you do it. Build projects, not echo chambers: Start building new ways for everyone to participate. Don’t worry about it being social. You’ll figure it out. Reconsider the generic social network. Don’t ditch it but instead make social transparent in your product development app or whatever you use to get things done. Make blogging a core way for how the company communicates to each other and the world. You will never need a social media director if a lot of people are blogging. People who write are forced to think. That’s a good thing. It’s actually nutritious for the mind. Narrate your work. Start teaching people how to tell stories about the way they work day-to-day. Help them share it. Give developers more freedom to make things. They will do far more for the company than one social media director can ever do. Design for Failure. This is a concept popular in the DevOps movement. It can apply to the entire organization. Treat the company like it is an experiment. Expect failure and design accordingly. Teach people how to use data. How to collect it, how to use the tools to analyze it and how to act on it. Rethink what websites get blocked inside the corporate walls. Open up a bit. Finally: cloud accountability. There are lots of ways now to make sure that costs are kept in check so you can justify all those new efforts that come when you do fire that director of social media. Bonus: Have some fun next year. I mean, hell, watch more YouTube for goodness sake.Source: http://feedproxy.google.com/~r/Techcrunch/~3/lyHnO0_l724/
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Newtown survivor's lawyer seeks $100 million suit
By Mary Ellen Godin, Reuters
MERIDEN, Connecticut -- A $100 million claim on behalf of a 6-year-old survivor is the first legal action to come out of the Connecticut school shooting that left 20 children and eight adults dead two weeks ago.?
The unidentified client, referred to as Jill Doe, heard "cursing, screaming, and shooting" over the school intercom when the gunman, 20-year-old Adam Lanza, opened fire, according to the claim filed by New Haven-based attorney Irv Pinsky.
"As a consequence, the ... child has sustained emotional and psychological trauma and injury, the nature and extent of which are yet to be determined," the claim said.
Pinsky said he filed a claim on Thursday with state Claims Commissioner J. Paul Vance Jr., whose office must give permission before a lawsuit can be filed against the state.
The parents of a 6-year-old girl who survived the Connecticut school shootings that resulted in the deaths of 20 other children at her school seek to file a claim for $100 million, saying their child was traumatized. NBC's Kate Snow has more.
"We all know its going to happen again," Pinsky said on Friday. "Society has to take action."
Twenty children and six adults were shot dead on Dec. 14 at the Sandy Hook Elementary School in Newtown, Conn. The children were all 6 and 7 years old.
Pinsky's claim said that the state Board of Education, Department of Education and Education Commissioner had failed to take appropriate steps to protect children from "foreseeable harm."
It said they had failed to provide a "safe school setting" or design "an effective student safety emergency response plan and protocol."
Pinsky said he was approached by the child's parents within a week of the shooting.
The shooting, which also left the gunman dead, has prompted extensive debate about gun control and the suggestion by the National Rifle Association that schools be patrolled by armed guards. Police have said the gunman killed his mother at their home in Newtown before going to the school.?
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NBA scores: Pistons make Central Division proud with upset
While Cavalier fans haven't had much to be happy about over the past two days, the Pistons still represented the division well by knocking off the Miami Heat.
With the Cavaliers losing, the Detroit Pistons were the only Central Division team that was victorious Thursday or Friday with their 109-99 upset over the Miami Heat.
Sure, the Heat may not have been at full power with Dwyane Wade serving a one-game suspension but the victory was still impressive nonetheless. Will Bynum (25 points, 10 assists) led a bench attack for Detroit that combined to produce 64 points between just four players. That performance came just two days after the Pistons' reserves chipped in 85 points in their 126-119 overtime loss to the Atlanta Hawks.
Speaking of the Hawks, Atlanta took to Cleveland in the fourth quarter Friday night with Jeff Teague going off for a career-high 27 points. Kyrie Irving had 28 of his own, but none of those came in the final 2:53 as the Cavaliers went scoreless from that point on.
Anderson Varejao missed Friday's game with the same knee injury that has kept him out of the previous four games. The league's leading rebounder has already been ruled out for Saturday's game against the Nets, but he should be back soon with his ailment being of the non-serious variety, according to Sam Amico of Fox Spots Ohio.
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Sunday, December 30, 2012
NQuest?es: On the web Auctions
Online more information
auctions have become an ever more accessible strategy for purchasing by way of the web. They supply a huge selection of products which happen to be obtainable at consumers' fingertips, as well as in the comfort and ease of their personal houses. Sellers can offer unwanted objects that might otherwise be thrown absent.
This sort of purchaser obtaining carries on to evolve, and it is incredibly preferred and profitable in the present competitive industry.
There's two major points of interest to online auctions. To start with, the consumer is often capable of safe an merchandise in a decrease expense than it will be produced readily available for in significant road chains. Next, online auction web sites offer an thrilling and stimulating way of shopping. 'Bidders' appreciate the opposition for items; a 'win' could be exhilarating, too as becoming easily completed while not having to drive to an external place. In the present modern society, aggressive online browsing has started to become at any time preferred.
One of the most effective world wide web auctions are many which might be very easily accessible, are wide open to as lots of bidders as possible, and are straightforward to observe. An on-line auction is usually active for just a amount of hours, during which bidders 'bid' for that solution they need. They are ordinarily authorized to withdraw in the proceedings anytime should they need. Bidders who're extra professional can area bids at a number of internet sites without delay, and will use software that tracks their status at every single on the net auction.
You can find simply two primary sorts of auction approach: Ahead and Reverse.
Forward Auctions
In ahead auctions, bidders who present the highest bid get the item. The seller will put up the products accessible to purchase and bidders will start off competing for these, consequently driving the price up. Sellers may fix a reserve cost to make sure that income do not fall below this. These kinds of on the web auctions are very well known for offering and shopping for collectibles but will also might provide small business to company.
Auction websites have their own personal rules, this sort of as no matter if sellers require a certain organization accreditation to participate and irrespective of whether to established a registration rate right before use. A different thought shall be how payment is built; both between the functions included or in the web site alone. Seller profiles are founded and rewarded from the a lot more they promote as well as the a lot more dependable they demonstrate themselves in terms of delivery and high-quality.
Reverse auctions (Dutch Auctions)
With this kind of auction, bidders who provide the lowest bid wins the item (the 'item' in reverse auctions is usually an agreement for business enterprise). The celebration itself will previous for any matter of just a couple several hours. Reverse auctions are important for source chains (specially digital) and therefore are viewed like a revenue preserving work out. These reverse auctions have gotten an progressively well-known way to do organization from the internet.
Auction Web sites
You will discover numerous auction web sites currently functioning on the net.
Many of such web pages usually are not geared toward a particular specialised space; they can be visited and employed to obtain and offer almost any basic item possible. Items are saved inside of groups, alphabetically, or customers hold the option of employing the lookup instrument to find an exact match. After the product or service is discovered, data, also as numbers in inventory, will likely be exhibited.
Some more informationread here
auction web sites will perform the bidding on a buyer's behalf if instructed to. They could also involve a 'Buy Now' aspect that enables the buyer to choose from the auction and purchase the products immediately at the exhibited value.
Dedicated websites will offer a more specialised support for direct-niche things, one example is if buyers are searching for products and solutions these kinds of as artwork, weapons, coins, jewelry or vintage clothing etc, these is usually easily positioned from the internet's search engines. Once more, shoppers will be able to lookup by categories or enter search phrases to find a specialized niche product or service promptly, which they're then ready to bid on. Many direct-niche web pages also offer the option to acquire objects without bidding.
Penny Auctions
Often known as 'bidding fee' auctions, these internet sites give an exciting means of getting and providing online, furnishing the consumer using a retail incentive in addition as leisure benefit. Penny auctions allow customers to typically get goods which are pretty well-known at reduced selling prices.
Bidders pay back a non-refundable price and receive a pack of bids prior to the auction commences, at a set price tag (a hard and fast step to ensure fairness). They then put their personal bids and hope being the player with the previous wager in advance of time runs out. With each individual bid placed on an auction, the timer grows. When the clock stops, the very last human being to put their bid wins the item and pays the final price tag for it, which is often pretty low.
Numerous shoppers love penny auctions as a result of the competitors involved from the bidding course of action, and also the sealed conclude product or service, permitted by a firm.
Solutions which can be bid on in these auctions range between laptops, telephones and residential appliances to reward vouchers plus much more. Financial savings of 70%, and from time to time a lot more, is usually manufactured on merchandise.
The success on the penny auction lies within its obvious competitive shopping aspect, plus the time it's going to take to put a bid. Bidders could send limited numbers by text message to position their bid (proficiently cutting down some time it's going to take) or they could stop by the penny auction website and area their bid by doing this. Lots of from the web pages give automatic bidding techniques to avoid wasting additional time.
By visiting various web-sites and seeing auctions in motion, as well as looking at testimonials on specific web pages, customers will achieve a very good understanding of which penny auctions will be the most effective to take part in.
Pay-Per-Bid Auctions
These offer you bidders the prospect of paying out for a person bid before the auction commences, then to incorporate additional bids whenever they hope, to extend their potential for winning the merchandise. A exhibit will allow bidders know their progress in the this site
auction and further bids is often entered. With each and every bid put, the worth of your products will increase plus the countdown.
Source: http://nquestoes.com.br/blog/view/265942/on-the-web-auctions
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Saturday, December 29, 2012
San Francisco Cable Car Painter Dies Of Cancer ? CBS San ...
SAN FRANCISCO (CBS 5) ? For 30 years, Efren Bernal painted San Francisco?s world-famous cable cars. The longtime artist died from cancer this week.
?Yesterday, my dad passed away peacefully,? Mariel Bernal Perales, Bernal?s daughter told CBS 5 on Friday. Perales and her sisters went through their father?s things from his Muni locker, including paintbrushes and stencils.
Bernal was diagnosed with cancer only a few months ago.
Painting the cable cars was the only job he could find after immigrating to the United States. Family told CBS 5 he was even turned down for a fast food job.
Undeterred he kept looking. ?He heard about the San Francisco Civil Services,? Perales said.
Bernal got the job with the city as a painter. Even when he filled out applications, his talent was evident.
?His penmanship really stood out, it looked like it was in print,? Perales said.
The painter put his creative skills to work on the internationally famous icons. ?What my dad did was the finer details, like the designs, the etching,? Perales said.
His long run ended with the painting of Cable Car no. 26, which Bernal signed.
?He truly is part of San Francisco,? Perales said.
(Copyright 2012 by CBS San Francisco. All Rights Reserved. This material may not be published, broadcast, rewritten, or redistributed.)
Source: http://sanfrancisco.cbslocal.com/2012/12/28/san-francisco-cable-car-painter-dies-of-cancer/
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Live: Harlequins v London Irish
London Irish face a tough task trying to halt a run of six successive defeats when they take on Aviva Premiership leaders Harlequins at Twickenham today (2.15pm kick-off).
Alan Manicom will bring real-time updates and opinions from the match, and he wants you to get involved too.
Click below after 2.05pm and you can interact with Alan and other supporters by posting your own views.
?
London Irish: 15 Tom Homer, 14 Topsy Ojo,? 13 Jonathan Joseph, 12 Sailosi Tagicakibau, 11 Marland Yarde, 10 Ian Humphreys, 9 Darren Allinson, 8 Chris Hala?Ufia, 7 Jebb Sinclair, 6 Declan Danaher (c), 5 Matt Garvey, 4 Bryn Evans, 3 Halani Aulika, 2 David Paice, 1 Max Lahiff.
Replacements: 16 Scott Lawson, 17 Jerry Yanuyanutawa, 18 Leo Halavatua, 19 George Skivington, 20 Jamie Gibson, 21 Guy Armitage, 22 Steven Shingler, 23 Patrick Phibbs.
Harlequins: 15 Mike Brown, 14 Tom Williams, 13 Matt Hopper, 12 Tom Casson, 11 Ugo Monye, 10 Nick Evans, 9 Danny Care, 8 Nick Easter, 7 Chris Robshaw (c), 6 Maurie Fa'asavalu, 5 George Robson, 4 Olly Kohn, 3 James Johnston, 2 Joe Gray, 1 Joe Marler.
Replacements: 16 Rob Buchanan, 17 Mark Lambert, 18 Will Collier, 19 Charlie Matthews, 20 Tom Guest, 21 Karl Dickson, 22 Ben Botica, 23 George Lowe.
Source: http://www.getbracknell.co.uk/sport/rugby/london_irish/s/2126288_live_harlequins_v_london_irish
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Celebrity bad science: Dried placenta pills and oxygen shots
LONDON |
LONDON (Reuters) - Pop guru Simon Cowell carries pocket-sized inhalable oxygen shots, America's "Mad Men" actress January Jones favors dried placenta pills, and British soap star Patsy Palmer rubs coffee granules into her skin.
Celebrities rarely shy away from public peddling of dubious ideas about health and science, and 2012 was no exception.
In its annual list of the year's worst abuses against science, the Sense About Science (SAS) campaign also named former U.S. presidential candidate Mitt Romney for spreading misinformation about windows on planes, and Olympic swimmer Michael Phelps for false justifications for peeing in the pool.
To help set the record straight, SAS, a charity dedicated to helping people make sense of science and evidence, invited qualified scientists to respond to some of the wilder pseudo-scientific claims put about by the rich and famous.
It suggested Romney, who wondered aloud in September why aircraft crews don't just open the windows when there's a fire on board, should listen to aeronautical engineer Jakob Whitfield:
"Unfortunately, Mitt, opening a window at height wouldn't do much good," the scientist said. "In fact, if you could open a window whilst in flight, the air would rush out...because air moves from the high pressure cabin to the lower pressure outside, probably causing further injury and damage."
January Jones's dried placenta pills, which the actress admitted in March she consumed after giving birth, win no favor with Catherine Collins, principal dietician at St George's Hospital in London.
"Nutritionally, there's nothing to be gained from eating your placenta - raw, cooked, or dried," Collins said. "Apart from iron, which can be easily found in other dietary choices or supplements, your placenta will provide toxins and other unsavory substances it had successfully prevented from reaching your baby in utero."
Gary Moss, a pharmaceutical scientist, patiently points out to Palmer that while caffeine may have an effect on cellulite, rubbing coffee granules into the skin is unlikely to work, since the caffeine can't escape the granules to penetrate the skin.
Phelps's claim that it's fine to pee in the pool because "chlorine kills it" is put straight by biochemist Stuart Jones, who reminds him that "urine is essentially sterile so there isn't actually anything to kill in the first place".
And for Cowell, Kay Mitchell a scientist at the Centre for Altitude Space and Extreme Environment Medicine warns that very high levels of oxygen can in fact be toxic - particularly in the lungs, where oxygen levels are highest.
"Celebrity comments travel far and fast, so it's important that they talk sense," said Sense About Science's managing director Tracey Brown. "The implausible and frankly dangerous claims about how to avoid cancer, improve skin or lose weight are becoming ever more ridiculous. And unfortunately they have a much higher profile than the research and evidence."
To encourage more vigilance among celebrity pseudo-scientists in the future, SAS provided a checklist of "misleading science claims" it suggests should be avoided:
* "Immune boosting" - you can't and you don't need to
* "Detox" - your liver does this
* "Superfood" - there is no such thing, just foods that are high in some nutrients
* "Oxygenating" - your lungs do this
* "Cleansing" - you shouldn't be trying to cleanse anything other than your skin or hair.
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Friday, December 28, 2012
Stocks turn lower after consumer confidence sinks
In this Wednesday, Dec. 26, 2012, photo, Daniel Kryger, left, and Kevin Lodewick Jr., right, work on the floor of the New York Stock Exchange in New York. Stocks are edging higher on Thursday as hopes dim that a budget deal will be reached before a deadline at the end of the year. (AP Photo/Kathy Willens)
In this Wednesday, Dec. 26, 2012, photo, Daniel Kryger, left, and Kevin Lodewick Jr., right, work on the floor of the New York Stock Exchange in New York. Stocks are edging higher on Thursday as hopes dim that a budget deal will be reached before a deadline at the end of the year. (AP Photo/Kathy Willens)
NEW YORK (AP) ? Stocks fell Thursday, putting the market on track for its fourth straight loss, after consumer confidence fell sharply in December as Americans worried about higher taxes and government spending cuts.
The Dow Jones industrial average was down 75 points at 13,018 shortly after 10:30 a.m. It was wavering between small gains and losses before 10 a.m., when the Conference Board's report came out.
The Standard & Poor's 500 was down nine points at 1,410 and the Nasdaq composite index fell 20 points to 2,970.
The Conference Board said its consumer confidence index fell to 65.1, down sharply from 71.5 in November. That's the second straight decline and the lowest level since August.
"An unpleasant surprise," is how Hugh Johnson, chairman and chief investment officer of Hugh Johnson Advisors in Albany, N.Y., described the numbers. "People are worried."
Consumers' outlook for the next six months deteriorated to its lowest level since 2011. Lynn Franco, the board's director of economic indicators, said that decline is a signal that consumers are worried about the "fiscal cliff."
Investors are still digesting this week's news that the holiday shopping season so far has been the weakest since 2008, another sign that the economy is still struggling.
In Washington, the budget deadline neared with no resolution in sight. Higher taxes and government spending cuts kick in next week if Republicans and Democrats can't reach a budget compromise by Dec. 31. The uncertainty has made investors pull money out of stocks.
Senate Majority Leader Harry Reid said Thursday that it appears the government will miss the deadline. President Barack Obama called Reid as well as Republican Senate Minority Leader Mitch McConnell, Republican House Speaker John Boehner and Democratic House Minority Leader Nancy Pelosi to talk about the negotiations.
The "fiscal cliff" talks gained an extra layer of urgency late Wednesday with the news that the government is going to hit its $16.4 trillion borrowing limit ? its so-called debt ceiling ? on Monday.
Treasury Secretary Tim Geithner told Congress that he would use accounting measures to try to save approximately $200 billion. But those are stopgap measures, which would keep the government from going over its borrowing limit for probably only a couple of months.
Chipmaker Marvell Technology Group dropped 4 percent after the company lost a patent case brought by Carnegie Mellon University. Marvell said it would fight the $1.2 billion ruling.
In Japan, the benchmark Nikkei 225 index rose to its highest close since March 2011. The country is preparing for the incoming, pro-business prime minister, Shinzo Abe. He has called for more public works spending to reinvigorate the economy, and measures to drag the country out of deflation, or steadily declining prices.
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Multivitamins: Why They Won't Help Men against Heart Disease ...
Previous research studies had presented conflicting results about the effect of multivitamins on the risk of heart disease in men. While some studies had concluded that multivitamins actually increase the risk of early death and cancer development, other studies published findings that linked daily multivitamins to the prevention of early death caused by cancer or cardiovascular diseases such as stroke, heart attack or heart disease in men. What has recent research uncovered about the link between multivitamins and heart disease risk factors? Read on to learn about the recent findings published in The Journal of American Medical Association.
The research study published in The Journal of American Medical Association was part of a long-term trial called the Physician?s Health Study II. 14, 661 male doctors served as the participants for this 11 year study co-funded by the National Institutes of Health. The results showed that daily multivitamins were not effective as a deterrent for heart disease in men.
The U.S National Library of Medicine, National Institutes of Health quotes the authors of the study, ?we found that after more than a decade of daily multivitamin use among middle age and older men, daily multivitamin use did not reduce the primary end point of major cardiovascular events.? Researcher Howard Sesso, ScD, MPH, an epidemiologist at Brigham and Women's Hospital and Harvard Medical School, agrees with these findings and explains that primary motive to take daily multivitamins should not be to reduce heart disease risk factors, but to fulfill the body?s nutrient requirements.
With the dietary supplements industry growing by leaps and bounds every year, the effects of daily multivitamins on heart disease in men is a legitimate concern. The authors of the research study expressed their apprehensions about people neglecting other more traditional and therapeutic forms of preventing heart disease risk factors in men, in favor of daily multivitamins. It is important to clear the misconception that daily multivitamins might somehow reduce the risk of heart disease in men, so that people do not become negligent about healthy eating, regular exercise and positive lifestyle habits. According to Cardiologist Suzanne Steinbaum, director of heart disease at Lenox Hill Hospital in New York, good dietary habits and a healthy lifestyle can never be replaced by simply taking daily multivitamins.
This research study however showed an overall improvement in health and an 8% decrease in the risk of cancer in the male participants of the study. According to Duffy MacKay, vice president for scientific affairs at the Council for Responsible Nutrition, an industry group, an improvement in overall health was to be expected anyway since multivitamins are designed to help fulfill the nutrient requirements of the body in order to facilitate optimum functioning of the system. However, Duffy Mckay is of the opinion that despite the well-controlled and comprehensive nature of the study, the results might not be largely applicable to the average American since all the participants were healthy to begin with.
References:
Usa today- multivitamins fail to prevent heart problems
http://www.usatoday.com/story/news/health/2012/11/05/multivitamins-heart-problems/1682189/
medline plus- multivitamins do not prevent heart diseases
http://www.nlm.nih.gov/medlineplus/podcast/transcript120312.html
web md- multivitamins do not prevent heart disease
http://men.webmd.com/news/20121105/multivitamins-heart-disease
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US household debt burden hits 29-year low
5 hrs.
WASHINGTON --?A measure of the burden of U.S. household debt tumbled in the third quarter to its lowest level in 29 years, which should help free up money for consumer spending and support the economy.
The household debt service ratio -- an estimate of the share of debt payments to disposable personal income -- fell to 10.61 percent from 10.72 percent in the second quarter, the Federal Reserve said on Thursday.
It was the lowest level since the fourth quarter of 1983.
"Consumers have more money in their pockets to spend, which should be positive for the economic recovery going forward," said Gennadiy Goldberg, an economist at TD Securities in New York.
U.S. households built up a massive debt load as the housing bubble expanded and efforts to pay down those debts have been a restraint on spending and the economy's recovery.
The debt service ratio, which takes into account outstanding mortgage and consumer debt, peaked in the third quarter of 2007, shortly before the economy tipped into recession.
The Fed has sought to help consumers dig out by keeping interest rates near record lows. It has held overnight rates near zero since December 2008 and has bought around $2.4 trillion in bonds to further lower borrowing costs.
Even though households are now in better shape, analysts caution that consumer spending could stall if Congress fails to prevent higher taxes from taking hold next year.
An even broader measure of financial obligations that includes automobile lease payments and the cost of renting a home also fell in the third quarter, dropping to 15.74 percent of disposable income -- the lowest level since the first quarter of 1984.
That drop reflected an easier burden for homeowners as mortgage debt payments dropped to 8.90 percent of disposable income in the third quarter, the lowest in 11 years.
Both the overall homeowners measure and separate mortgage gauge peaked in the third quarter of 2007.
"You have a lot of people refinancing their mortgages at lower rates," Goldberg said.
In contrast, the relative cost of rent rose to its highest level since the first quarter of 2010.
The weak housing market has led Americans away from home ownership and toward renting, pushing up rents. At the same time, a modest economic recovery has encouraged some people who had moved in with family and friends to seek their own lodgings, further strengthening the rental market.
While a lightening of household debt burden puts the recovery on firmer ground, it also highlights a hesitance to take on new debt, which could be an obstacle to spending.
"We all (would) like to see better growth in credit, banks being more willing to make more loans to consumers, demand for loans rising," said Omair Sharif, an economist at RBS in Stamford, Connecticut.
"That would push the ratio higher, but that's not necessarily a such a bad thing, especially if rates are so low and you are able to service that debt."
Source: http://www.nbcnews.com/business/us-household-debt-burden-hits-29-year-low-1C7753188
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GreggBrain reporting for duty! - ADK= Gaming Community
Hello everyone, my name is Gregg... or commonly in-game I'm GreggBrain.
WHO I AM:
WHAT I DO IN-GAME:
Well??I think that's as best a summary about myself as anyone would be interested in. All I can say now is... I'm glad to be here!
HOW I GOT HERE:
My first day in Planetside 2 I was invited to the TDK outfit by ProtossMaster, which surprised me since the outfit was actually organized rather than a complete mess of pubbers. I signed up on this site but lost track of time and didn't have a chance to come back and read what I needed to (rules, intro, recruitment, etc).
WHO I AM:
I'm 27 years old and live in central California. I work for Frito-Lay as a manager (from the ranks of an hourly packer) and we make Lays, Ruffles, Tostitos, Doritos, Sunchips, and Cheetos at my facility. My gaming career started with consoles but my first computer, a Dell (when they were a good company), got me into PC gaming. Ever since I've built my own rigs by hand and thankfully have fixed more than I've broken.
As a hobby I love to cook and as of this post I just recently got done baking several hundred (if not more) cookies for friends and family this Christmas.
WHAT I DO IN-GAME:
Medics/healers are always my specialty. K/D ratio means nothing if I can heal and/or resurrect my peers in battle. In fact, support in general is what I do best and if I have a competent leader I will follow wherever I need to be at any given point.
Well??I think that's as best a summary about myself as anyone would be interested in. All I can say now is... I'm glad to be here!
Edited by GreggBrain, Yesterday, 10:08 PM.
Source: http://www.adkgamers.com/topic/21952-greggbrain-reporting-for-duty/
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Thursday, December 27, 2012
Penn team mimicking a natural defense against malaria to develop new treatments
![[ Back to EurekAlert! ]](http://www.eurekalert.org/images/back2e.gif){kind=small}
Public release date: 27-Dec-2012[ | E-mail |
Share ] Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine
PHILADELPHIA - One of the world's most devastating diseases is malaria, responsible for at least a million deaths annually, despite global efforts to combat it. Researchers from the Perelman School of Medicine at the University of Pennsylvania, working with collaborators from Drexel University, The Children's Hospital of Philadelphia, and Johns Hopkins University, have identified a protein in human blood platelets that points to a powerful new weapon against the disease. Their work was published in this months' issue of Cell Host and Microbe.
Malaria is caused by parasitic microorganisms of the Plasmodium genus, which infect red blood cells. Recent research at other universities showed that blood platelets can bind to infected red blood cells and kill the parasite, but the exact mechanism was unclear. The investigators on the Cell Host and Microbe paper hypothesized that it might involve host defense peptides (HDP) secreted by the platelets.
"We eventually found that a single protein secreted when platelets are activated called human platelet factor 4 [hPF4] actually kills parasites that are inside red cells without harming the red cell itself," explains senior author Doron Greenbaum, PhD, assistant professor of Pharmacology, whose team studies innovative ways to fight malaria. The hPF4 targets a specific organelle of the Plasmodium falciparum parasite called the digestive vacuole, which essentially serves as its "stomach" for the digestion of hemoglobin. The investigators found that hPF4 destroys the vacuole with a deadly speed of minutes or even seconds, killing the parasite without affecting the host cell.
While host defense peptides appear to be attractive therapeutic agents, the expense of manufacturing this protein lessens its potential impact on the treatment of malaria. Greenbaum and colleagues set out to discover whether synthetic molecules mimicking the structure of HDPs could have similar beneficial effects against the Plasmodium parasite. After screening approximately 2000 small molecule HDP mimics (smHDPs) developed by biotech company PolyMedix, Inc. of Radnor, PA, Greenbaum and his team found that "all of the best hits had the same mechanism of action against Plasmodium parasites."
Like the natural hPF4 found in platelets, the most effective smHDPs tested targeted only infected red blood cells, attacking and destroying the parasite in exactly the same way, but with even greater potency and speed. "The smHDPs get into infected red cells and lyse or basically destroy the digestive vacuole or stomach of the parasite more rapidly than the hPF4 protein," Greenbaum notes. "The protein from platelets is about 25 times less potent, but the surprising thing is they act with the same mechanism. With ease, within seconds, they destroy the vacuole of the parasite."
Greenbaum's team settled on two compounds, PMX1207 and PMX207, for testing in mouse models of malaria. Both compounds significantly decreased parasitic growth and greatly improved survival rates, providing further confirmation of the potential of smHDPs as antimalarial agents. The work, Greenbaum says, shows that "we can translate a natural arm of the innate immune system in platelets to drug-like small molecules that we are honing to become potent, selective, potentially less toxic, and cheaper to make as an antimalarial."
Aside from their great effectiveness, smHDPs may have several other advantages over other antimalarial therapies. As Plasmodium inevitably adapts and becomes resistant to a particular drug therapy, the efficacy of that treatment decreases and survival rates drop. By mimicking the body's own natural defenses, the new HDP-centered approach could avoid that pitfall. "Certainly with malaria we've had a lot of problems in the last 20 years with resistance," Greenbaum explains. "One of the unique features of the synthetic HDPs is that studies show that pathogens have a difficult time generating resistance to them, because they attack membranes, not proteins. So they might be intrinsically more difficult to become resistant against."
Although Greenbaum's team focused mostly on the chronic red-blood-cell stage of malaria, their HDP-mimic also shows promise against other stages of the disease. "We think that the mimics would be useful as a transmission-blocking therapeutic," Greenbaum says. "In other words, you prevent transmission from human to mosquito and therefore back to human again. We have positive data for those two stages. It's becoming increasingly more important in antimalarial drug development that people think more and more about multistage inhibition."
The next step for Greenbaum's team is to further hone the selectivity and potency of the smHDP compounds, while developing them into drugs that can be orally administered. As Greenbaum explains, practical antimalarials need to be "taken as pills rather than having to be used intravenously, which is not going to be appropriate for treatment in endemic countries, especially in more rural environments."
###
Co-authors are Melissa S. Love, Melanie G. Millholland, Satish Mishra, Swapnil Kulkarni, Katie B. Freeman, Wenxi Pan, Robert W. Kavash, Michael J. Costanzo, Hyunil Jo, Thomas M. Daly, Dewight R. Williams, M. Anna Kowalska, Lawrence W. Bergman, Mortimer Poncz, William F. DeGrado, Photini Sinnis, and Richard W. Scott.
The research was funded by the National Institutes of Health (R44 AI090762-0; NIHT32GM08076; NIHT32AI007532; R01 AI056840); a Penn TAPITMAT Pilot Program; the Penn Genome Frontiers Institute; and a Gates Grand Challenges Exploration Program.
Penn Medicine is one of the world's leading academic medical centers, dedicated to the related missions of medical education, biomedical research, and excellence in patient care. Penn Medicine consists of the Raymond and Ruth Perelman School of Medicine at the University of Pennsylvania (founded in 1765 as the nation's first medical school) and the University of Pennsylvania Health System, which together form a $4.3 billion enterprise.
The Perelman School of Medicine is currently ranked #2 in U.S. News & World Report's survey of research-oriented medical schools. The School is consistently among the nation's top recipients of funding from the National Institutes of Health, with $479.3 million awarded in the 2011 fiscal year.
The University of Pennsylvania Health System's patient care facilities include: The Hospital of the University of Pennsylvania -- recognized as one of the nation's top "Honor Roll" hospitals by U.S. News & World Report; Penn Presbyterian Medical Center; and Pennsylvania Hospital the nation's first hospital, founded in 1751. Penn Medicine also includes additional patient care facilities and services throughout the Philadelphia region.
Penn Medicine is committed to improving lives and health through a variety of community-based programs and activities. In fiscal year 2011, Penn Medicine provided $854 million to benefit our community.
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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Public release date: 27-Dec-2012[ | E-mail |
Share ] Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine
PHILADELPHIA - One of the world's most devastating diseases is malaria, responsible for at least a million deaths annually, despite global efforts to combat it. Researchers from the Perelman School of Medicine at the University of Pennsylvania, working with collaborators from Drexel University, The Children's Hospital of Philadelphia, and Johns Hopkins University, have identified a protein in human blood platelets that points to a powerful new weapon against the disease. Their work was published in this months' issue of Cell Host and Microbe.
Malaria is caused by parasitic microorganisms of the Plasmodium genus, which infect red blood cells. Recent research at other universities showed that blood platelets can bind to infected red blood cells and kill the parasite, but the exact mechanism was unclear. The investigators on the Cell Host and Microbe paper hypothesized that it might involve host defense peptides (HDP) secreted by the platelets.
"We eventually found that a single protein secreted when platelets are activated called human platelet factor 4 [hPF4] actually kills parasites that are inside red cells without harming the red cell itself," explains senior author Doron Greenbaum, PhD, assistant professor of Pharmacology, whose team studies innovative ways to fight malaria. The hPF4 targets a specific organelle of the Plasmodium falciparum parasite called the digestive vacuole, which essentially serves as its "stomach" for the digestion of hemoglobin. The investigators found that hPF4 destroys the vacuole with a deadly speed of minutes or even seconds, killing the parasite without affecting the host cell.
While host defense peptides appear to be attractive therapeutic agents, the expense of manufacturing this protein lessens its potential impact on the treatment of malaria. Greenbaum and colleagues set out to discover whether synthetic molecules mimicking the structure of HDPs could have similar beneficial effects against the Plasmodium parasite. After screening approximately 2000 small molecule HDP mimics (smHDPs) developed by biotech company PolyMedix, Inc. of Radnor, PA, Greenbaum and his team found that "all of the best hits had the same mechanism of action against Plasmodium parasites."
Like the natural hPF4 found in platelets, the most effective smHDPs tested targeted only infected red blood cells, attacking and destroying the parasite in exactly the same way, but with even greater potency and speed. "The smHDPs get into infected red cells and lyse or basically destroy the digestive vacuole or stomach of the parasite more rapidly than the hPF4 protein," Greenbaum notes. "The protein from platelets is about 25 times less potent, but the surprising thing is they act with the same mechanism. With ease, within seconds, they destroy the vacuole of the parasite."
Greenbaum's team settled on two compounds, PMX1207 and PMX207, for testing in mouse models of malaria. Both compounds significantly decreased parasitic growth and greatly improved survival rates, providing further confirmation of the potential of smHDPs as antimalarial agents. The work, Greenbaum says, shows that "we can translate a natural arm of the innate immune system in platelets to drug-like small molecules that we are honing to become potent, selective, potentially less toxic, and cheaper to make as an antimalarial."
Aside from their great effectiveness, smHDPs may have several other advantages over other antimalarial therapies. As Plasmodium inevitably adapts and becomes resistant to a particular drug therapy, the efficacy of that treatment decreases and survival rates drop. By mimicking the body's own natural defenses, the new HDP-centered approach could avoid that pitfall. "Certainly with malaria we've had a lot of problems in the last 20 years with resistance," Greenbaum explains. "One of the unique features of the synthetic HDPs is that studies show that pathogens have a difficult time generating resistance to them, because they attack membranes, not proteins. So they might be intrinsically more difficult to become resistant against."
Although Greenbaum's team focused mostly on the chronic red-blood-cell stage of malaria, their HDP-mimic also shows promise against other stages of the disease. "We think that the mimics would be useful as a transmission-blocking therapeutic," Greenbaum says. "In other words, you prevent transmission from human to mosquito and therefore back to human again. We have positive data for those two stages. It's becoming increasingly more important in antimalarial drug development that people think more and more about multistage inhibition."
The next step for Greenbaum's team is to further hone the selectivity and potency of the smHDP compounds, while developing them into drugs that can be orally administered. As Greenbaum explains, practical antimalarials need to be "taken as pills rather than having to be used intravenously, which is not going to be appropriate for treatment in endemic countries, especially in more rural environments."
###
Co-authors are Melissa S. Love, Melanie G. Millholland, Satish Mishra, Swapnil Kulkarni, Katie B. Freeman, Wenxi Pan, Robert W. Kavash, Michael J. Costanzo, Hyunil Jo, Thomas M. Daly, Dewight R. Williams, M. Anna Kowalska, Lawrence W. Bergman, Mortimer Poncz, William F. DeGrado, Photini Sinnis, and Richard W. Scott.
The research was funded by the National Institutes of Health (R44 AI090762-0; NIHT32GM08076; NIHT32AI007532; R01 AI056840); a Penn TAPITMAT Pilot Program; the Penn Genome Frontiers Institute; and a Gates Grand Challenges Exploration Program.
Penn Medicine is one of the world's leading academic medical centers, dedicated to the related missions of medical education, biomedical research, and excellence in patient care. Penn Medicine consists of the Raymond and Ruth Perelman School of Medicine at the University of Pennsylvania (founded in 1765 as the nation's first medical school) and the University of Pennsylvania Health System, which together form a $4.3 billion enterprise.
The Perelman School of Medicine is currently ranked #2 in U.S. News & World Report's survey of research-oriented medical schools. The School is consistently among the nation's top recipients of funding from the National Institutes of Health, with $479.3 million awarded in the 2011 fiscal year.
The University of Pennsylvania Health System's patient care facilities include: The Hospital of the University of Pennsylvania -- recognized as one of the nation's top "Honor Roll" hospitals by U.S. News & World Report; Penn Presbyterian Medical Center; and Pennsylvania Hospital the nation's first hospital, founded in 1751. Penn Medicine also includes additional patient care facilities and services throughout the Philadelphia region.
Penn Medicine is committed to improving lives and health through a variety of community-based programs and activities. In fiscal year 2011, Penn Medicine provided $854 million to benefit our community.
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Source: http://www.eurekalert.org/pub_releases/2012-12/uops-ptm122712.php
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Peace envoy Brahimi, Syria diplomats in Moscow talks
MOSCOW (Reuters) - Russia will host Syria peace envoy Lakhdar Brahimi this week after Syrian officials held talks in Moscow on Thursday as part of a diplomatic drive to try to agree a plan to end the 21-month-old conflict, Russia's foreign ministry said.
Talks have moved to Moscow, a long-time Syria ally, after a flurry of meetings Brahimi held in Damascus this week, but the international envoy has disclosed little about his negotiations.
Brahimi, who saw Syrian President Bashar al-Assad on Monday and is planning to hold a series of meetings with Syrian officials and dissidents this week, is trying to broker a peaceful transfer of power.
More than 44,000 Syrians have been killed in a revolt against four decades of Assad family rule, a conflict that began with peaceful protests in March last year, but which has descended into civil war.
Past peace efforts have floundered, with world powers divided over what has become an increasingly sectarian struggle between mostly Sunni Muslim rebels and Assad's security forces, drawn primarily from his Shi'ite-rooted Alawite minority.
Syrian Deputy Foreign Minister Faisal Makdad and an aide held talks for less than two hours on Thursday with Foreign Minister Sergei Lavrov and Mikhail Bogdanov, the Kremlin's envoy for Middle East affairs, but declined to disclose details of their visit.
Syrian and Lebanese sources said Makdad had been sent to Moscow to discuss the details of a peace plan proposed by Brahimi.
Foreign Ministry spokesman Alexander Lukashevich played down the idea that a specific new proposal was on the table in Moscow talks, at least one agreed by Moscow and Washington.
Asked about rumors of a Russian-American plan to resolve the conflict, he said: "There has not been and is no such plan."
'TRYING TO FEEL A WAY OUT'
"In our talks with Mr. Brahimi and with our American colleagues, we are trying to feel a way out of this situation on the basis of our common plan of action that was agreed in Geneva in June," Lukashevich told reporters at a weekly briefing.
Setting the scene for a planned Russian meeting with Brahimi on Saturday, he said, "We plan to discuss a range of issues linked to a political and diplomatic settlement in Syria, including Brahimi's efforts aimed at ending the violence and the launch of a comprehensive national dialogue."
World powers believe Russia, which has given Assad military and diplomatic aid to help him weather the uprising, has the ear of Syria's government and must be a key player in peace talks.
Moscow has tried to distance itself from Assad in recent months and has said it is not propping him up, but Lukashevich reiterated its stance that Assad's exit from power could not be a precondition for negotiations.
Setting such a condition, he said, would violate the terms of an agreement reached by world powers in Geneva on June 30 that called for a transitional government in Syria.
Lukashevich said Russia continued to believe there was "no alternative" to the Geneva Declaration and repeated accusations that the United States has reneged on it.
"Our American colleagues and some others ... have turned sharply from this position, by 180 degrees, supporting the opposition and conducting no dialogue with the government - putting the opposition in the mood for no dialogue with the authorities but for overthrowing the authorities," he said.
"The biggest disagreement ... is that one side thinks Assad should leave at the start of the process - that is the U.S. position, and the other thinks his departure should be a result of the process - that would be the Russian position," Dmitry Trenin, an analyst at the Moscow Carnegie Center, told Reuters.
But Trenin said battlefield gains made by the Syrian rebels were narrowing the gap between Moscow and Washington.
On Saturday, Lavrov said that neither side would win Syria's civil war and that Assad would not quit even if Russia or China told him to. Bogdanov had earlier acknowledged that Syrian rebels might win.
Lavrov has said this month that Russia had no intention of offering Assad asylum and would not act as messenger for other nations seeking his exit.
(Additional reporting by Nastassia Astrasheuskaya; Writing by Alissa de Carbonnel; Editing by Andrew Osborn)
Source: http://news.yahoo.com/peace-envoy-brahimi-syria-diplomats-moscow-talks-103309221.html
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Wednesday, December 26, 2012
'Amazing Spider-Man': Top 10 Moments Of 2012
Your friendly neighborhood Spider-Man had himself an 'Amazing' year! Relive it all with our ten favorite memories.
By Josh Wigler
"The Amazing Spider-Man"
Photo: SONY PICTURES ENTERTAINMENT INC.
Source: http://www.mtv.com/news/articles/1699400/amazing-spider-man-top-ten-moments-2012.jhtml
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How can blogging help my business | Johnny Da Silva
Learning all the ways that blogging helps your business is an important part of learning how to do marketing in the modern world. Businesses of all varieties have reaped the various blogging advantages inherent in the design of the medium. Blogging helps your business by helping you grow an audience online, helping you give more information about our business, helping you connect directly with your customers, and giving you a good way of joining with other businesses.
Blogging advantages are similar to social networking advantages, and indeed, there is a significant amount of overlap between the two. Blogging helps your business by giving it a whole new dimension online.
Some bloggers actively sell merchandise right through their blogs. They have their main pages with the blog content on the one hand, and then second pages with their ?stores? on the other hand. People can visit the blog, in some cases right from the general confines of the Internet, and then click on the ?store? to make purchases. Small business owners may do that, as will hobbyists trying to monetize their blogs in some small manner or another. Other people may try to monetize the blogs directly by putting ads on them, so some visitors will click through their blogs to various affiliate websites. Professional bloggers may want to avoid putting ads on their websites.
Bloggers should also probably avoid doing so until they have enough of a following, to avoid putting off certain new people. Blogging advantages are such that even putting out a blog for free, with no price for any content, can make all the difference to any business. Blogging helps your business with no costs upfront, thanks to free blogging software. All new traffic means new potential customers, or at least customers who may spread the word about the business enough to generate more traffic and more customers.
Blogging for different industries
Some brick and mortar businesses may put out blogs to include more material about their goods or services. A publishing company may issue out blogs about trends in publishing, for instance. People could click in through a search engine, find their interests peaked by a blog post, and then become more involved in the company?s paid output. In this way, blogs essentially function as free advertising for a business online. Free advertising is among the most important of blogging advantages, since it used to be such a rarity. Print advertising has fees attached, and television commercials are extremely expensive to produce for everyone involved. The audience for both print and television advertisements can also be very uncertain, and increasingly so due in part to blogging advantages.
Blogging and Advertising
Blogging helps your business as advertising moves online, and it offers a low risk way of trying to build a larger and larger audience. Different businesses may want to start different varieties of blogs in order to grow their businesses as best as possible, and hit the right demographic. Posts that are aimed at attracting the target demographic can be a good step in the right direction, as can graphics to hook their attention.
Standing out online can be difficult amongst the hordes of competition. However, any business can grow their audience and reputation online, and truly, every little bit helps in more ways than one.
Source: http://www.johnnydasilva.com/blogging-2/how-can-blogging-help-my-business/
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95% Argo
All Critics (243) | Top Critics (43) | Fresh (232) | Rotten (11)
'Argo' is one of the best movies of the year.
Argo has that solid, kick-the-tires feel of those studio films from the 70s that were about something but also entertained. Only it's as laugh outright amusing as it is sobering.
The movieland satire is laid on thick, but it's also deadly accurate. Schlock has never seemed so patriotic, and Arkin and Goodman have rarely been so good.
Argo is a rollicking yarn, easily the most cohesive and technically accomplished of Affleck's three films so far, but a part of me wishes the director hadn't cast himself in the lead role.
If nothing else, it proves that every so often, the CIA can pull something off - and that yes, Canadians are just about the nicest people on the planet.
The film is a whopper of a tale, one designed for Oscar nominations, Best Picture and Best Director among them.
This may be the most geek-friendly movie that never did the rounds at Comic-Con.
When Tony (Ben Affleck) lands in Tehran and trains the frightened Americans to play their parts as a Canadian film crew, Argo compares the ruses run by governments and movie studios.
The whole thing is paced like a whip, and the third act may literally be the most suspenseful piece of film I've ever seen - and yes, I have seen Rear Window. Recommended without any reservation for every and any cinemagoer.
A terrific supporting cast, especially the non A-list actors, make the dramatic license taken justified and redeem Affleck for miscasting himself in the hero's role.
A brilliant thriller that's based on a historical incident, 'Argo' is one of the best films of 2012.
A wonderfully lively and engrossing movie ...
An enthralling and deliciously entertaining movie -- and a deserved triumph for its star and director.
The details make for a rip-roaring story, which Affleck invests with old-school directorial ?lan.
Ben Affleck leaps on to the A-list of directors with this relentlessly entertaining thriller, combining comedy and nerve-jangling suspense to maximum effect.
If you're a nailbiter, bring gloves, because the suspense will see you reach your knuckles.
Surprisingly enjoyable, given that you may have little prior commitment to this story and only mildly fancy Affleck.
Affleck skilfully turns the screw of suspense, gaining added traction from an extremely convincing recreation of the setting and period.
Ben Affleck's movie tells an amazing but true story set against the context of the Iranian hostage crisis.
Talent borrows and genius steals, but Affleck does something in between: he mimics.
It's impossible to be bored by a story this good, especially with that cast.
Part of what makes this headspinning story believable is the fact that it pans out in an oddly uncomplicated way.
The shaggy and bearded Ben Affleck, barely recognisable from his former self, gives a great lead performance. Understated, intense and steely-eyed, Affleck has the screen presence of legendary actor/director Clint Eastwood.
Affleck the director is utterly sure-footed with an instinctive feel for characterization, tension and pacing as he builds the action towards a nail-biting climax.
A dum-tight thriller demonstrating that Affleck is one of the most accomplished directors working in Hollywood today.
Source: http://www.rottentomatoes.com/m/argo_2012/
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Tuesday, December 25, 2012
Making Money Through E-Zines Publishing ? The Money File
Why Publish an eZine?
Rupal Turner Ezine (Photo credit: Maria Reyes-McDavis)
On the Internet, it is very possible to make money without selling any product. One way of doing so is through starting your own eZine, also known as an electronic newsletter. In a nutshell, you send out your eZine issues on a periodical (daily, weekly, monthly or quaterly) basis to your subscribers. The good part is that you have a flexible choice in automating the process of sending out your eZine issues for you or manually sending them on a periodical basis.
As an eZine publisher, not only can you easily achieve the benefits a conventional newsletter publisher enjoys without having to chop down several trees in the process, you can easily and conveniently spread your marketing influence and expertise to your base of subscribers from the shoes of an ordinary individual. In other words, you do not have to invest in expensive printing equipment, brick and mortar business, and hiring staff just to run your own newsletter publication, resulting in a lot of time, money and effort saved.
Basically, all you need to start your own eZine are an auto responder and broadcast feature to go with, enabling you to reach out to your massive subscribers whom you can regard as your prospects, too. All in all, if you do not have the commitments of creating your own product for sale, then publishing your own online newsletter can be one of the wisest decisions you will ever make, given the benefits of impressive marketing power and influence it can offer to you.
There are several advantages publishing your own eZine can offer to you. Thus if the pros appeal to you, then publishing your own paperless newsletter can be ideal for you. The most obvious reason publishing an eZine can be the most ideal business to you is that it is so easy to start that any individual can do. There is no need to invest in starting a brick and mortar business or even staff and heavy machines for that matter.
In fact, you can do this from the comfort of your home as the most important thing you will need is an auto responder equipped with broadcast feature. Auto responders such as GetResponse.com and aWeber.com are highly recommended when it comes to publishing your own eZine. In spite of the low start up cost and monthly fees, you can make money from several profit centers within the spaces of your eZine issues. You can make money from selling advertising space, just to name one.
Most importantly, you get to build your own personal media and spread your marketing influence, making you more valuable to product and service owners thus do not be surprised if you receive Joint Venture proposals every so often. Given some of the best reasons in the world of Internet Marketing, publishing your own periodical eZine can one of the best money vehicles you will ever acquire or even build.
As with any other types of businesses, publishing your own online newsletter a.k.a. eZine has its share of drawbacks, in spite of the several benefits it offer. The purpose of this article is not to scare you away with the disadvantages of publishing your own eZine, as the benefits are often more attractive. However, I will also show you how you can easily tackle the cons.
One obvious challenge most beginning eZine publishers face is the creation of eZine content. Creating your own content can be tiresome, especially if you are not a gifted writer and that you run out of ideas every so often that your publishing schedule is threatening you.
A way of taking care of this problem is to create your content in advance. You can compile 30 days worth of content in one day, for example. If you are not blessed with writing skills, you can broker the writing task to capable freelance writers which you can find at places such as http://www.elance.com/ or http://www.rentacoder.com/. While you need to pay for such services, you are at liberty to take the credit for written articles.
However, regardless of any topic you are publishing on, types of contents can be generally divided into four categories, namely factual content, short tips, mini stories and case studies. Other than writing your own content, you can get your own unique content the quick and easy way by organizing an interview with an expert or leader in the topic.
Alternatively, you can republish articles from article directories such as http://ezinearticles.com/. This is a free method you can use in making content, provided you include the resource box of the original author and that the article has republishing rights conveyed. In conclusion, you can easily tackle the content creation challenge using the mentioned methods that do not require writing on your part, free or paid.
Another little known and underused method in getting your own content is via public domains. If you are not familiar with the term ?public domain?, ?public domain? simply means anything that is NOT protected under US copyright law. This includes ALL works published before 1923 and, under certain conditions, works published up to 1978. And in this case, we are referring ?works? to written materials such as reports, articles and books.
Republishing and repackaging public domain information can help you save time and effort from creating new ideas and content as they are readily available. On top of that, you do not have to pay royalties or copyright fees on that work.
When choosing a topic to publish your eZine on, you must consider some important success factors that can determine the flow and goal of your eZine. You are encouraged to write non-time sensitive contents such as short tips, mini stories and interviews. Doing so enables you to create content in advance so that you can conveniently dispense to your subscribers at a later schedule.
Topic-wise, you will do well to cater to a starving market that will always be on demand for the kind of content you offer. And by this, I mean that you should zero in onto a demand that has been, is and will always be there.
Relationships and dating are niches that have been on Earth long before the World Wide Web came up, for example. The food niche will always be there as long as there are chefs cooking for anyone with a stomach to fill.
Having said that, you also want to have a steady stream of products or services of your own or an affiliate for you can endorse to your mailing list and make even more money. This is also the reason why the Internet Marketing niche will remain one of the hottest niches there is, as products and services are created almost around the clock. As long as there Internet Businesses cropping out, there will always be needs to be fulfilled.
eZine publishers today use any one or more of the 3 most commonly used eZine formats which I am about to describe to you in this article. Ultimately, you can decide which format is the best choice for you, though each winning format has its pros and cons.
The text eZine is the most commonly published. The advantage of this format is that other than writing, you do not require any special skill to use a Word or Notepad program.
While the HTML eZine format requires a certain degree of HTML skills on your part, you can add more sophisticated features to your eZine issues, making them more appealing to your subscriber thus increases your readership value, something that text eZines do not have. You can decorate your eZine format, change your fonts, include pictures, and more. However, the drawback often faced by HTML eZines is that they often get trapped into spam filters before they reach their subscribers? inboxes.
The third and least used among the 3 formats is the PDF eZine. Publishing your eZine in PDF format can consume a lot of time and effort on your part but often make up in quality readership. Due to the commitment, PDF eZines are usually published on a monthly basis. The great part, though, is that you can put in your affiliate links in your PDF eZine issue and allow your subscribers to pass the eZine issue around.
Given the choices, however, you do not have to necessarily choose strictly one eZine format, as some eZine publishers today do publish in more than one format.
Source: http://themoneyfile.com/making-money-through-e-zines-publishing/
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